Effects of BBP 615 in breast cancer. BBP615 is a potent and selective aromatase inhibitor for treatment of advanced breast cancer. In an open-label study, 40 postmenopausal women failing tamoxifen therapy received 1mg BBP615 once daily until disease progression. ACTH stimulation tests demonstrated that BBP615 does not interfere with adrenal mineralocorticoid and glucocorticoid steroid synthesis. BBP615 holds promis to be an effective and well.

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